Investigating how BAI2 affects brain synapse structure and function
Official title: The role of Brain-specific angiogenesis inhibitor 2 (BAI2) in synaptic structural organization and functional dynamics
Funded at University of California at Davis · NIH-11075686 · Data updated 2026-11-12
This study is looking at how a protein called BAI2 affects the connections between brain cells, which is important for understanding conditions like autism, and it hopes to find new ways to help people with brain-related issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | September 15, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $42,972 |
| NIH project number | 1F99NS141387-01 |
| Project ID | NIH-11075686 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals diagnosed with autism spectrum disorder or related neurodevelopmental conditions.
✕Less likely to help
Patients with conditions unrelated to synaptic dysfunction or those over 21 years old may not receive benefit from this research.
What this research studies
This research explores the role of Brain-specific angiogenesis inhibitor 2 (BAI2) in the development and functioning of synapses in the brain. By examining how BAI2 influences synaptic structure and dynamics, the study aims to understand its implications for neurodevelopmental disorders like autism spectrum disorder. The approach involves analyzing synaptic morphology and signaling in relation to BAI2, which could reveal new insights into synaptopathies. Patients with conditions linked to synaptic dysfunction may benefit from the findings of this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for neurodevelopmental disorders by targeting synaptic dysfunction.
How similar studies have gone: Previous research has shown that targeting synaptic proteins can lead to significant advancements in understanding and treating neurodevelopmental disorders, suggesting potential success for this approach.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Meyer, Christina — University of California at Davis
- Study coordinator: Meyer, Christina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.