Investigating how autistic adults perceive and communicate pain

Pain sensitivity and endogenous pain modulation in autistic adults

NIH-funded research Ohio State University · NIH-10818606

This study is looking at how autistic adults feel and talk about pain differently than non-autistic adults, with the goal of finding better ways to help manage pain for autistic individuals as they get older.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-10818606 on NIH RePORTER

What this research studies

This research focuses on understanding how autistic adults experience pain differently compared to non-autistic adults, particularly in the context of communication challenges. The study aims to explore the intensity of pain reported by autistic individuals and the associated anxiety, as well as the neural responses to pain. By examining these factors, the research seeks to improve pain management strategies for autistic adults, especially as they age and face chronic pain conditions. The methodology includes assessing pain perception and communication abilities in a diverse group of autistic adults.

Who could benefit from this research

Good fit: Ideal candidates for this research are autistic adults aged 21 and older who experience chronic pain or have difficulty communicating about their pain.

Not a fit: Patients who are not autistic or those who do not experience chronic pain may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management and treatment strategies tailored specifically for autistic adults.

How similar studies have performed: Previous research has indicated that autistic individuals experience pain differently, suggesting that this approach could yield valuable insights, although this specific focus on adult pain perception is relatively novel.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.