Investigating how atypical MAP kinases affect cell movement and growth
Atypical MAP Kinase Signal Transduction
['FUNDING_R15'] · OKLAHOMA STATE UNIVERSITY STILLWATER · NIH-10577709
This study is looking at special proteins in amoebas that help control how cells grow and move, which could help us understand similar processes in humans and other complex organisms.
Quick facts
| Phase | ['FUNDING_R15'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OKLAHOMA STATE UNIVERSITY STILLWATER (nih funded) |
| Locations | 1 site (STILLWATER, UNITED STATES) |
| Trial ID | NIH-10577709 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding atypical MAP kinases, which are important for regulating cell growth and movement in eukaryotic organisms. The study uses the amoeba Dictyostelium as a model to explore how these kinases are activated and how they influence cell behavior. By examining the interactions between these kinases and specific transcription factors, the research aims to uncover the mechanisms that drive cell motility and differentiation. This could provide insights into how similar processes work in more complex organisms, including humans.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to abnormal cell growth or movement, such as cancer or certain genetic disorders.
Not a fit: Patients with conditions unrelated to cell motility or growth regulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for manipulating cell movement and growth, which may have implications for treating various diseases.
How similar studies have performed: While the specific focus on atypical MAP kinases is relatively novel, previous research on conventional MAP kinases has shown significant success in understanding cell signaling pathways.
Where this research is happening
STILLWATER, UNITED STATES
- OKLAHOMA STATE UNIVERSITY STILLWATER — STILLWATER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HADWIGER, JEFFREY A — OKLAHOMA STATE UNIVERSITY STILLWATER
- Study coordinator: HADWIGER, JEFFREY A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.