Investigating how atrazine affects hormone regulation through the kisspeptin pathway
Official title: Developmental neuroendocrine toxicity targeting the kisspeptin pathway
Funded at Purdue University · NIH-10747443 · Data updated 2026-11-12
This study is looking at how a common weed killer called atrazine might affect hormones in our bodies, especially those related to growth and reproduction, to help us understand how it could impact health and well-being.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Purdue University NIH-funded |
| Lab location | 1 site (West Lafayette, United States) |
| Project start | December 1, 2022 |
| Project end | November 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $187,744 |
| NIH project number | 5R21ES034966-02 |
| Project ID | NIH-10747443 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who may have been exposed to atrazine or are concerned about its effects on health.
✕Less likely to help
Patients who have not been exposed to atrazine or who do not have concerns related to hormonal disruptions may not benefit from this research.
What this research studies
This research explores the effects of atrazine, a common herbicide, on the endocrine system, particularly focusing on the kisspeptin pathway. Researchers will examine how atrazine disrupts hormone regulation and its potential impacts on developmental, reproductive, and neurobehavioral outcomes. By identifying the kisspeptin system as a key regulator, the study aims to understand the broader implications of atrazine exposure on health. Patients may benefit from insights into how environmental toxins affect hormonal balance and overall well-being.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of health issues related to hormonal disruptions caused by environmental toxins.
How similar studies have gone: Previous studies have shown that environmental toxins can disrupt endocrine functions, suggesting that this research could build on established findings.
Where this research is happening
-
Purdue University
West Lafayette, United States Active
Researchers
- Principal investigator: Freeman, Jennifer L. — Purdue University
- Study coordinator: Freeman, Jennifer L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.