Investigating how arginase 1 affects vision loss from retinal injuries

Role of Arginase 1 in Retinal Ischemia-Reperfusion Injury

NIH-funded research Univ of Arkansas for Med Scis · NIH-10792867

This study is looking at how a protein called arginase 1 might help protect your eyes from damage caused by conditions like diabetic retinopathy and glaucoma, with the hope of finding new ways to improve vision and prevent vision loss.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of Arkansas for Med Scis NIH-funded
Lab location1 site (Little Rock, United States)
Project IDNIH-10792867 on NIH RePORTER

What this research studies

This research focuses on understanding the role of arginase 1 in retinal ischemia-reperfusion injury, which is a significant cause of vision loss in conditions like diabetic retinopathy and glaucoma. The project aims to explore the mechanisms behind retinal damage and identify potential new therapeutic targets that could help protect vision. By studying the protective effects of arginase 1 in retinal cells, the research seeks to develop strategies that could mitigate the harmful effects of ischemic injury. Patients may benefit from advancements in treatment options that arise from this research.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with retinal ischemia-related diseases, such as diabetic retinopathy or glaucoma.

Not a fit: Patients with retinal conditions not related to ischemia or those without any retinal diseases may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapies that help preserve vision in patients suffering from retinal ischemia-related conditions.

How similar studies have performed: Previous research has shown promising results in understanding the role of arginase in retinal diseases, suggesting that this approach has potential for success.

Where this research is happening

Little Rock, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.