Investigating how anesthetics affect calcium channels in the brain
Voltage-gated calcium channels as target for anesthetics
This study is looking at how general anesthetics affect certain channels in the brain that play a role in pain, awareness, and memory, with the goal of finding better ways to manage pain and improve anesthesia for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11092231 on NIH RePORTER |
What this research studies
This research explores the mechanisms by which general anesthetics work, particularly focusing on voltage-gated calcium channels (VGCCs) in the brain. It aims to understand how these channels influence pain sensation, consciousness, and memory during anesthesia. By studying the effects of anesthetics on VGCCs, the research seeks to uncover new insights into pain management and anesthesia procedures. Patients may benefit from improved anesthetic techniques and pain control based on the findings.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals undergoing surgical procedures who require anesthesia.
Not a fit: Patients who are not undergoing surgery or do not require anesthesia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer anesthetic practices, enhancing pain management during surgeries.
How similar studies have performed: Previous research has shown promising results in understanding the role of calcium channels in pain processing, indicating potential for success in this area.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Todorovic, Slobodan M. — University of Colorado Denver
- Study coordinator: Todorovic, Slobodan M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.