Investigating how amelogenin nanoribbons contribute to enamel development
Amelogenin Nanoribbons In Enamel Development And Engineering
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11054620
This study is looking at how a special protein called amelogenin helps form and strengthen the enamel on your teeth, so we can learn more about keeping your smile healthy and strong.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-11054620 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the role of amelogenin, a key protein in enamel formation, and how it self-assembles into nanoribbons that guide the growth of mineral structures in teeth. By studying the interactions between amelogenin and other components in the enamel matrix, researchers aim to uncover the mechanisms behind enamel mineralization and its structural integrity. The approach includes advanced 3D modeling and analysis of the enamel's extracellular matrix to better understand how these processes occur at a molecular level.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with enamel-related dental issues or those interested in advancements in dental treatments.
Not a fit: Patients without any enamel defects or those not seeking dental treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for dental enamel defects and better strategies for tooth repair and regeneration.
How similar studies have performed: Previous research has shown promising results in understanding enamel biomineralization, indicating that this approach has potential for significant advancements.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HABELITZ, STEFAN FRIEDRICH — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: HABELITZ, STEFAN FRIEDRICH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.