Investigating how altered nutrient metabolism affects pancreatic cancer
Role of Altered Nutrient Metabolism in Pancreatic Cancer
['FUNDING_R01'] · BOSTON CHILDREN'S HOSPITAL · NIH-11059860
This study is looking at how changes in nutrient use, especially certain compounds called polyamines, affect the growth of pancreatic cancer cells, with the goal of finding new treatments that are kinder to patients while still fighting the cancer.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON CHILDREN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11059860 on ClinicalTrials.gov |
What this research studies
This research focuses on pancreatic ductal adenocarcinoma (PDAC), a highly aggressive form of pancreatic cancer with a poor prognosis. The study aims to explore the role of altered nutrient metabolism, particularly polyamines, in the growth and survival of cancer cells. By understanding these metabolic changes, the researchers hope to develop novel therapeutic strategies that minimize side effects while effectively targeting cancer cells. Patients may benefit from new treatment options that are less harmful to normal tissues.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with pancreatic ductal adenocarcinoma.
Not a fit: Patients with other types of cancer or those who are not diagnosed with pancreatic cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatment options for pancreatic cancer patients.
How similar studies have performed: Previous research has shown some promise in targeting metabolic pathways in cancer, but this specific approach to pancreatic cancer is relatively novel.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON CHILDREN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KALAANY, NADA Y. — BOSTON CHILDREN'S HOSPITAL
- Study coordinator: KALAANY, NADA Y.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.