Investigating how ALIX protein functions in cell processes and its modifications
The Functional Interplay Between Phase Separation, Fibrillization, and Posttranslational Modifications of ALIX
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10896377
This study is looking at a protein called ALIX, which helps cells communicate and manage their life processes, to see how it changes shape and interacts with other molecules, which could help us understand more about how cells work together.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10896377 on ClinicalTrials.gov |
What this research studies
This research focuses on the ALIX protein, which plays a crucial role in various cellular processes such as cell signaling and apoptosis. The project aims to understand how ALIX forms different structures, like liquid-like condensates and amyloid fibrils, and how these structures are influenced by chemical modifications. By studying these processes in mammalian cells, the research seeks to uncover the mechanisms that regulate ALIX's functions and its interactions with other molecules. This could provide insights into how cellular communication and signaling are maintained.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions linked to dysregulation of cell signaling or apoptosis.
Not a fit: Patients with conditions unrelated to cell signaling or apoptosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for diseases related to cell signaling and apoptosis.
How similar studies have performed: Other research has shown promising results in understanding protein interactions and modifications, suggesting potential for success in this area as well.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DESHMUKH, LALIT — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: DESHMUKH, LALIT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.