Investigating how alcohol use disorder affects brain health differently in men and women
Sex Differences in Alcohol Use Disorder Neurodegeneration using Multimodal PET and DTI Neuroimaging
This study is looking at how alcohol use disorder affects the brains of men and women differently, using special brain scans to help find better treatment options for everyone.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10873851 on NIH RePORTER |
What this research studies
This research focuses on understanding how alcohol use disorder (AUD) leads to brain changes that differ between sexes. Using advanced imaging techniques like positron emission tomography (PET) and diffusion tensor imaging (DTI), the study will analyze brain function and structure in individuals with AUD. By comparing data from both men and women, the research aims to uncover specific neurobiological differences that could inform tailored treatment strategies. Participants will undergo brain scans to help identify these differences and contribute to a larger understanding of AUD.
Who could benefit from this research
Good fit: Ideal candidates for participation include men and women diagnosed with alcohol use disorder, as well as healthy individuals matched by age and sex.
Not a fit: Patients who do not have alcohol use disorder or are not within the specified age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, sex-specific treatments for individuals with alcohol use disorder.
How similar studies have performed: Previous research has shown promising results in understanding sex differences in neurodegeneration, suggesting that this approach could yield valuable insights.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Zakiniaeiz, Yasmin — Yale University
- Study coordinator: Zakiniaeiz, Yasmin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.