Investigating how alcohol use affects tuberculosis infection and disease in people living with HIV
The Role of Alcohol Use in Incident TB Infection and Active TB Disease Among Persons Living with HIV
This study is looking at how drinking alcohol might affect the risk of getting tuberculosis (TB) and developing active TB in people living with HIV in Uganda, so we can find better ways to help keep them healthy.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10904857 on NIH RePORTER |
What this research studies
This research focuses on understanding the relationship between alcohol consumption and tuberculosis (TB) infection among individuals living with HIV. It aims to explore how heavy alcohol use influences the risk of acquiring new TB infections and the progression to active TB disease, particularly after receiving tuberculosis preventive therapy (TPT). The study will involve a cohort of individuals in Uganda, where high rates of HIV and TB coexist, and will assess the impact of alcohol on TB outcomes. By identifying the effects of alcohol use, the research seeks to inform targeted interventions that could help reduce TB risk in this vulnerable population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are 21 years or older and engage in heavy alcohol use.
Not a fit: Patients who do not consume alcohol or those who are not living with HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing tuberculosis in individuals living with HIV who consume alcohol heavily.
How similar studies have performed: Previous research has indicated a significant correlation between alcohol use and poorer TB outcomes in HIV-positive populations, suggesting that this study builds on established findings.
Where this research is happening
Boston, United States
- Boston Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Hahn, Judith Alissa — Boston Medical Center
- Study coordinator: Hahn, Judith Alissa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.