Investigating how air pollution affects Lewy Body Dementia
Official title: Determine the role of atmospheric particulate matter pollutants in contributing to Lewy Body Dementia
Funded at Johns Hopkins University · NIH-10662930 · Data updated 2026-11-12
This study is looking at how air pollution might be linked to Lewy Body Dementia, especially in older adults, to help us understand which pollutants could affect brain health and how to reduce risks for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | April 15, 2023 |
| Project end | March 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $2,296,059 |
| NIH project number | 1RF1AG079487-01A1 |
| Project ID | NIH-10662930 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults, particularly those living in urban areas with high levels of air pollution and experiencing cognitive decline.
✕Less likely to help
Patients who do not have cognitive decline or those living in areas with low air pollution may not receive direct benefits from this research.
What this research studies
This research explores the connection between atmospheric particulate matter pollutants and Lewy Body Dementia (LBD). It aims to identify specific pollutants that may contribute to the development and progression of dementia, particularly in older adults. By analyzing epidemiological data and examining the effects of air pollution on the central nervous system, the study seeks to uncover the underlying mechanisms linking environmental factors to cognitive decline. Patients may benefit from a better understanding of how to mitigate risks associated with air pollution.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies and interventions for Lewy Body Dementia related to air pollution exposure.
How similar studies have gone: Previous research has indicated a correlation between environmental pollutants and dementia, suggesting that this approach has potential for significant findings.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Mao, Xiaobo — Johns Hopkins University
- Study coordinator: Mao, Xiaobo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.