NIH-funded research R01 grant

Investigating how air pollution affects childhood asthma and lung function

Official title: Childhood Asthma: Disease Course and Lung Function Trajectories and Air Pollution Exposure

Funded at University of Texas at Austin · NIH-11018592 · Data updated 2026-11-12

This study is looking at how air pollution affects asthma in kids, and it involves 300 children from different backgrounds to see how their lung health and asthma symptoms change over time, with the hope of finding ways to help them breathe better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin
NIH-funded
Lab location1 site (Austin, United States)
Project startFebruary 1, 2024
Project endNovember 30, 2028
Funding year2025
Award (this year)$658,724
NIH project number5R01ES035131-02
Project IDNIH-11018592 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-11 years who have been diagnosed with asthma and live in areas with varying levels of air pollution.

Less likely to help

Patients who do not have asthma or are outside the age range of 0-11 years may not benefit from this research.

What this research studies

This research focuses on understanding how exposure to air pollution, particularly particulate matter, influences the severity and progression of asthma in children. By conducting a prospective cohort study involving 300 multi-ethnic children, researchers will measure lung function, asthma severity, and specific sources and compositions of air pollution over time. The goal is to identify environmental factors that contribute to worsening asthma and lung function decline, which could help in developing targeted interventions for affected children.

Why it matters

Potential benefit: If successful, this research could lead to improved management strategies for childhood asthma, potentially reducing long-term lung disease risk.

How similar studies have gone: Previous studies have shown that air pollution negatively impacts lung function in children, suggesting that this research could build on established findings.

Where this research is happening

  • University of Texas at Austin
    Austin, United States
    Active

Researchers

  • Principal investigator: Matsui, Elizabeth C. — University of Texas at Austin
  • Study coordinator: Matsui, Elizabeth C.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.