Investigating how air pollution affects cellular stress and the potential of antioxidants to help
Official title: Non-Invasive Probing Cellular Oxidative Stress and Antioxidants Therapeutic Effectiveness
Funded at Utah State University · NIH-10652764 · Data updated 2026-11-12
This study is looking at how air pollution from things like diesel exhaust can harm our heart and lung health, and it will also explore if eating foods rich in antioxidants can help protect us from these harmful effects.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Utah State University NIH-funded |
| Lab location | 1 site (Logan, United States) |
| Project start | June 15, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $414,664 |
| NIH project number | 1R15HL168697-01 |
| Project ID | NIH-10652764 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals exposed to high levels of air pollution, particularly those with respiratory or cardiovascular conditions.
✕Less likely to help
Patients who are not exposed to air pollution or do not have related health conditions may not benefit from this research.
What this research studies
This research focuses on understanding the harmful effects of particulate matter from air pollution, particularly diesel exhaust, on human health, especially regarding cardiovascular and pulmonary diseases. It aims to explore how these pollutants induce oxidative stress in cells and whether dietary antioxidants can mitigate these effects. The study will utilize advanced measurement technologies to assess cellular responses to pollutants in both laboratory and living systems. By examining different regions of the respiratory tract, the research seeks to clarify how various cells react to air pollution.
Why it matters
Potential benefit: If successful, this research could lead to improved therapeutic strategies using antioxidants to protect against air pollution-related health issues.
How similar studies have gone: Previous research has shown promising results in using antioxidants to combat oxidative stress, indicating potential for success in this approach.
Where this research is happening
-
Utah State University
Logan, United States Active
Researchers
- Principal investigator: Zhou, Anhong — Utah State University
- Study coordinator: Zhou, Anhong
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.