Investigating how air pollution affects Alzheimer's disease and dementia.
Air Pollution and Alzheimer's Dementia: Neuropathologic and Olfactory Mechanisms in Multi-Ethnic Longitudinal Cohorts
This study is looking at how air pollution might be connected to Alzheimer's disease and other types of dementia, and it's for anyone interested in understanding how the air we breathe could affect brain health as we age.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10769882 on NIH RePORTER |
What this research studies
This research explores the potential link between air pollution and the development of Alzheimer's disease and related dementias. It aims to understand how exposure to air pollutants may influence neurocognitive aging through systematic evaluations of cognitive function and dementia in participants over time. The study will include detailed postmortem assessments of brain pathology and the olfactory system, which may serve as a pathway for environmental toxins to impact brain health. By utilizing data from diverse longitudinal cohorts, the research seeks to fill gaps in knowledge regarding the mechanisms by which air pollution affects dementia.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults, particularly those living in areas with high levels of air pollution.
Not a fit: Patients who are younger or do not have concerns related to cognitive decline or dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for Alzheimer's disease related to environmental factors.
How similar studies have performed: Previous research has indicated potential links between environmental factors and cognitive decline, suggesting that this approach may yield valuable insights.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Weuve, Jennifer — Boston University Medical Campus
- Study coordinator: Weuve, Jennifer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.