Investigating how aging genes affect optic nerve regeneration
Targeting aging genes and pathways to promote optic nerve regeneration
This study is looking at how certain genes related to aging affect the healing of optic nerves, with the hope of finding new ways to help people improve their vision after nerve damage.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10759381 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of aging-related genes in the regeneration of optic nerves. It explores how certain genes, which are known to influence the ability of neurons to grow and repair themselves, are also linked to the aging process. By examining these connections, the research aims to identify potential therapeutic targets that could enhance optic nerve regeneration in patients. The approach includes studying specific genes and pathways involved in cellular aging and their impact on nerve repair mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing optic nerve damage or degeneration, particularly those related to aging.
Not a fit: Patients with optic nerve injuries not related to aging or those with irreversible damage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve vision recovery for patients with optic nerve injuries.
How similar studies have performed: Previous research has shown promising results in targeting aging genes for nerve regeneration, indicating a potential for success in this approach.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Wan, Mei — Johns Hopkins University
- Study coordinator: Wan, Mei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.