Investigating how aging cells contribute to inflammation
Yale Murine-TMC on Immune Cell Senescence Derived Inflammation
This study is looking at how aging cells in the body can cause inflammation, using mice to find clues that could help us understand how these cells affect our health as we get older.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10901925 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of senescent cells, which are aging cells that can contribute to inflammation in the body. Using advanced technologies, the team will analyze mouse models to identify specific biomarkers associated with these cells and their impact on various tissues. By mapping the presence and effects of senescent cells in different environments, the research aims to uncover mechanisms of aging and inflammation. This could lead to new insights into how these processes affect health and disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults or individuals experiencing chronic inflammatory conditions related to aging.
Not a fit: Patients who are young or do not have any signs of chronic inflammation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing age-related inflammation and improving health outcomes for older adults.
How similar studies have performed: Previous research has shown promising results in understanding the role of senescent cells in aging and inflammation, indicating that this approach has potential for significant findings.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Dixit, Vishwa Deep — Yale University
- Study coordinator: Dixit, Vishwa Deep
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.