Investigating how aging biomarkers relate to Alzheimer's disease and physical disability
Official title: Methods to Test Biomarkers of Aging as Shared Determinants of Alzheimers Disease and Related Dementias and Physical Disability
Funded at University of Maryland Baltimore · NIH-10984462 · Data updated 2026-11-12
This study is looking at how certain biological factors related to aging might lead to Alzheimer's disease and physical disabilities in older adults, with the hope of finding ways to prevent these issues and improve health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | February 1, 2023 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $653,435 |
| NIH project number | 5R01AG079854-03 |
| Project ID | NIH-10984462 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 65 and older who may be at risk for Alzheimer's disease or related dementias.
✕Less likely to help
Patients under the age of 65 or those without any signs of cognitive decline or physical disability may not benefit from this research.
What this research studies
This research focuses on understanding the biological factors that contribute to Alzheimer's disease and related dementias (ADRD) as well as physical disabilities in older adults. By examining biomarkers associated with aging, the study aims to identify shared determinants that could help in preventing cognitive decline and physical disability. The approach involves rigorous epidemiological methods to explore the connections between aging processes and the onset of these conditions. Patients may be assessed for various biological markers that reflect their aging process, which could lead to targeted interventions.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing Alzheimer's disease and physical disabilities in older adults.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between aging biomarkers and cognitive decline, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Maryland Baltimore
Baltimore, United States Active
Researchers
- Principal investigator: Shardell, Michelle Denise — University of Maryland Baltimore
- Study coordinator: Shardell, Michelle Denise
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.