Investigating how aging and inflammation affect Alzheimer's disease in women
MAE-WEST RSC - Eicosanoids Profiling Core
This study is looking at how aging and diseases like Alzheimer's affect men and women differently, especially focusing on how stress and certain chemicals in the body might play a role, with the goal of finding ways to help women as they get older.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10903837 on NIH RePORTER |
What this research studies
This research focuses on understanding the differences in aging and disease development between men and women, particularly in relation to Alzheimer's disease and related dementias. It examines how chronic stress and inflammatory mediators, known as eicosanoids, may contribute to these differences. By profiling these eicosanoids, the research aims to uncover the underlying mechanisms that lead to a higher prevalence of Alzheimer's disease in women as they age. The findings could help identify potential interventions to reduce the burden of age-related diseases in women.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing early signs of Alzheimer's disease or related dementias, particularly those over the age of 65.
Not a fit: Patients who are male or those who do not have any signs of Alzheimer's disease or related dementias may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted therapies that specifically address the unique aging processes in women, potentially reducing the incidence of Alzheimer's disease.
How similar studies have performed: Previous research has shown promising results in understanding sex differences in aging and disease, suggesting that this approach could yield valuable insights.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Jain, Mohit — Cedars-Sinai Medical Center
- Study coordinator: Jain, Mohit
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.