Investigating how aging affects women's health and disease risk
The Microvascular Aging and Eicosanoids - Women's Evaluation of Systemic Aging Tenacity (MAE-WEST) ("You are never too old to become younger!") Specialized Center for Research Excellence (SCORE)
This study is looking at how women age differently than men, especially when it comes to chronic diseases like Alzheimer's and heart failure, to help find better ways to support women's health as they get older.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10903833 on NIH RePORTER |
What this research studies
This research focuses on understanding how women age differently than men, particularly in relation to chronic diseases like Alzheimer's and heart failure. It explores the role of microvascular aging and systemic inflammation in these differences, aiming to uncover the biological mechanisms that contribute to multi-organ dysfunction in women. By studying eicosanoids, which are bioactive lipids involved in inflammation, the research seeks to identify how these factors influence women's health outcomes as they age. The findings could lead to better-targeted interventions for age-related diseases in women.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing age-related health issues, particularly those related to Alzheimer's disease and other chronic conditions.
Not a fit: Patients who are not women or those who do not have age-related chronic diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for chronic diseases that disproportionately affect women as they age.
How similar studies have performed: Previous research has shown promising results in understanding sex differences in aging and chronic diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Cheng, Susan — Cedars-Sinai Medical Center
- Study coordinator: Cheng, Susan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.