Investigating how aging affects specific immune cells in older adults
Studying the significance of memory CD8+ T cells differentially expressing IL-7 receptor alpha in human aging
This study is exploring how getting older affects your immune system, especially looking at certain immune cells in people aged 65 and up, to see if there are differences that might help explain health issues as we age.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10890418 on NIH RePORTER |
What this research studies
This research focuses on understanding how aging influences the immune system, particularly looking at memory CD8+ T cells in older adults. By analyzing blood samples from individuals aged 65 and older, the study aims to identify differences in immune cell populations that may contribute to age-related health issues. The researchers are particularly interested in the expression of the IL-7 receptor alpha on these cells, which could provide insights into their function and role in inflammation and immunity as people age.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older, particularly those interested in understanding their immune health.
Not a fit: Patients younger than 65 years or those without any age-related immune concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing age-related diseases, including Alzheimer's disease.
How similar studies have performed: Previous research has indicated that changes in immune cell populations with age can significantly impact health, suggesting that this approach may yield valuable insights.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Kang, Insoo — Yale University
- Study coordinator: Kang, Insoo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.