Investigating how aging affects muscle health using advanced MRI techniques
Development and Application of T1rho Dispersion Imaging of Aging Muscle
['FUNDING_OTHER'] · VANDERBILT UNIVERSITY MEDICAL CENTER · NIH-11127705
This study is looking at new ways to use MRI to see how our muscles change as we get older, starting with tests on animals and then moving to people, to help us understand and improve muscle health as we age.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY MEDICAL CENTER (nih funded) |
| Locations | 1 site (NASHVILLE, UNITED STATES) |
| Trial ID | NIH-11127705 on ClinicalTrials.gov |
What this research studies
This research focuses on developing and applying new magnetic resonance imaging (MRI) techniques to better understand muscle deterioration associated with aging. By creating detailed images that quantify changes in muscle tissue, the study aims to identify specific pathological changes that occur as people age. The researchers will first test these methods on rodent models and then validate them in human subjects, providing insights into muscle health and function. This innovative approach could lead to improved diagnostic tools for age-related muscle conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over the age of 21 who are experiencing age-related muscle deterioration.
Not a fit: Patients who are under 21 or do not have any age-related muscle conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic methods for assessing muscle health in older adults, potentially improving treatment strategies.
How similar studies have performed: Other research has shown promise in using advanced MRI techniques to study muscle health, indicating that this approach may yield valuable insights.
Where this research is happening
NASHVILLE, UNITED STATES
- VANDERBILT UNIVERSITY MEDICAL CENTER — NASHVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ADELNIA, FATEMEH — VANDERBILT UNIVERSITY MEDICAL CENTER
- Study coordinator: ADELNIA, FATEMEH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: age associated chronic disease, age associated chronic disorder