Investigating how aging affects lung immunity
Data Science Core
This study is looking at how our lung's immune system changes as we get older, especially when fighting off viruses, to help us find better ways to keep our lungs healthy as we age.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jackson Laboratory NIH-funded |
| Lab location | 1 site (Bar Harbor, United States) |
| Project ID | NIH-11059963 on NIH RePORTER |
What this research studies
This research focuses on understanding the decline of lung tissue-resident immunity in older individuals. It involves creating a dedicated Data Science Core to manage and analyze large volumes of data related to immune responses in the lungs. The project aims to identify molecular signatures and immune pathways that change with age, particularly in response to viral infections. By integrating and sharing this data, the research seeks to enhance our understanding of how age impacts lung immunity and inform future therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who may be experiencing changes in lung function or immune response.
Not a fit: Patients who are younger and do not have any age-related immune issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for age-related declines in lung immunity, potentially reducing the risk of respiratory infections in older adults.
How similar studies have performed: Other research has shown promising results in understanding age-related immune changes, indicating that this approach has potential for success.
Where this research is happening
Bar Harbor, United States
- Jackson Laboratory — Bar Harbor, United States (Active)
Researchers
- Principal investigator: Chaussabel, Damien — Jackson Laboratory
- Study coordinator: Chaussabel, Damien
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.