Investigating how aging affects liver cancer in mice
Core B: Mouse Models of Aging and Cancer
This study is looking at how getting older affects the risk of liver cancer in mice, and it’s testing different treatments and genetic changes to find ways to help prevent this type of cancer as we age.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sanford Burnham Prebys Medical Discovery Institute NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10908390 on NIH RePORTER |
What this research studies
This research focuses on understanding the relationship between aging and liver cancer development using mouse models. It involves various interventions, including genetic modifications and treatments, to explore how age-related changes can influence cancer onset. The study will monitor key health parameters in mice, such as body weight and tumor growth, while also utilizing advanced imaging techniques and tissue analysis. By examining these factors, the research aims to uncover potential strategies to prevent liver cancer linked to aging.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for liver cancer, particularly older adults who may be experiencing age-related health changes.
Not a fit: Patients who are not at risk for liver cancer or those who are not elderly may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new prevention strategies for liver cancer in aging populations.
How similar studies have performed: Previous research has shown promising results in using animal models to study cancer and aging, indicating that this approach has potential for success.
Where this research is happening
La Jolla, United States
- Sanford Burnham Prebys Medical Discovery Institute — La Jolla, United States (Active)
Researchers
- Principal investigator: Sacco, Alessandra — Sanford Burnham Prebys Medical Discovery Institute
- Study coordinator: Sacco, Alessandra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.