Investigating how aging affects bleeding risk in von Willebrand disease
The Von Willebrand Disease Aging and Bleeding Correlation (VWD ABC) Study
['FUNDING_OTHER'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10877727
This study is looking at how age affects bleeding risk in adults with von Willebrand disease, and it aims to help improve care for people living with this condition by understanding their bleeding tendencies better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10877727 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the relationship between age and bleeding risk in patients with von Willebrand disease (VWD), a hereditary bleeding disorder. The study will enroll adults aged 18 and older from multiple Hemophilia Treatment Centers, where participants will undergo assessments using a bleeding evaluation tool and provide blood samples for laboratory analysis. The goal is to determine how age influences von Willebrand factor levels and bleeding tendencies, which could lead to improved management strategies for patients with VWD.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 18 and older diagnosed with type 1 von Willebrand disease.
Not a fit: Patients with bleeding disorders other than von Willebrand disease or those under 18 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of bleeding risks in older patients with von Willebrand disease.
How similar studies have performed: Previous research has shown promising results in understanding bleeding disorders, but this specific focus on aging in von Willebrand disease is relatively novel.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SEAMAN, CRAIG D — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: SEAMAN, CRAIG D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.