NIH-funded research R21 grant

Investigating how age and hearing loss affect brain processing of sound

Official title: Age and hearing loss effects on subcortical neural encoding

Funded at Medical University of South Carolina · NIH-11049107 · Data updated 2026-11-12

This study is looking at how older adults struggle to understand speech in noisy places because of hearing loss, and it aims to learn more about how their brains process sounds differently as they age.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina
NIH-funded
Lab location1 site (Charleston, United States)
Project startMarch 1, 2023
Project endFebruary 28, 2026
Funding year2025
Award (this year)$188,750
NIH project number5R21DC020559-03
Project IDNIH-11049107 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults experiencing age-related hearing loss and younger adults for comparison.

Less likely to help

Patients with normal hearing who are not experiencing age-related hearing loss may not benefit from this research.

What this research studies

This research explores the challenges older adults face with speech recognition, especially in noisy environments, due to age-related hearing loss. It focuses on understanding how the brain's auditory system, particularly the midbrain, responds to sounds and how this response changes with age and hearing impairment. By examining the relationship between brain activity and hearing difficulties, the study aims to identify the underlying mechanisms that contribute to these challenges. The research employs advanced techniques to measure brain responses to sound stimuli in different age groups.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments and interventions for speech recognition difficulties in older adults with hearing loss.

How similar studies have gone: Previous research has shown promising results in understanding auditory processing in older adults, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Medical University of South Carolina
    Charleston, United States
    Active

Researchers

  • Principal investigator: Mcclaskey, Carolyn Marie — Medical University of South Carolina
  • Study coordinator: Mcclaskey, Carolyn Marie

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.