Investigating how age and hearing loss affect brain processing of sound

Age and hearing loss effects on subcortical neural encoding

NIH-funded research Medical University of South Carolina · NIH-11049107

This study is looking at how older adults struggle to understand speech in noisy places because of hearing loss, and it aims to learn more about how their brains process sounds differently as they age.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-11049107 on NIH RePORTER

What this research studies

This research explores the challenges older adults face with speech recognition, especially in noisy environments, due to age-related hearing loss. It focuses on understanding how the brain's auditory system, particularly the midbrain, responds to sounds and how this response changes with age and hearing impairment. By examining the relationship between brain activity and hearing difficulties, the study aims to identify the underlying mechanisms that contribute to these challenges. The research employs advanced techniques to measure brain responses to sound stimuli in different age groups.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults experiencing age-related hearing loss and younger adults for comparison.

Not a fit: Patients with normal hearing who are not experiencing age-related hearing loss may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments and interventions for speech recognition difficulties in older adults with hearing loss.

How similar studies have performed: Previous research has shown promising results in understanding auditory processing in older adults, suggesting that this approach could yield valuable insights.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.