Investigating how activated platelets affect breathing problems in COPD patients
Platelet Activation Pathways and Respiratory Morbidity in COPD
This study is looking at how active platelets might affect breathing problems in people with COPD who don’t have heart disease, hoping to find new ways to help improve their lung health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11010816 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of activated platelets in chronic obstructive pulmonary disease (COPD), a serious lung condition. By measuring platelet activation and reactivity in individuals with COPD who do not have cardiovascular disease, the study aims to uncover how these platelets may contribute to respiratory issues. The approach involves using advanced imaging techniques to assess platelet behavior and its potential impact on patient outcomes. This could lead to new treatment options that specifically target platelet activation pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with COPD who do not have any cardiovascular disease.
Not a fit: Patients with significant cardiovascular disease or other major comorbidities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new therapeutic strategies for managing respiratory symptoms in COPD patients.
How similar studies have performed: Previous studies have suggested a link between platelet activation and respiratory morbidity in COPD, but this research aims to provide more specific insights into the mechanisms involved.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Fawzy, Ashraf — Johns Hopkins University
- Study coordinator: Fawzy, Ashraf
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.