Investigating how acid sensing affects alcohol use disorders and panic disorders
Acid sensing associated mechanisms in AUD and comorbid panic
['FUNDING_OTHER'] · UNIVERSITY OF ILLINOIS AT CHICAGO · NIH-11030286
This study is looking at how alcohol affects our feelings and behaviors, especially for people dealing with alcohol use disorders and panic disorder, to find new ways to help them feel better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT CHICAGO (nih funded) |
| Locations | 1 site (Chicago, UNITED STATES) |
| Trial ID | NIH-11030286 on ClinicalTrials.gov |
What this research studies
This research explores the complex effects of alcohol on the body, particularly how it alters behaviors and emotions, leading to alcohol use disorders (AUDs) and comorbid psychiatric conditions like panic disorder (PD). The study focuses on a specific mechanism involving acid-base balance and a novel microglial acid-sensor called TDAG8, which may play a role in both AUD and PD. By understanding how these mechanisms interact, the research aims to uncover new insights into treatment options for individuals suffering from these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with alcohol use disorders who may also experience panic disorder.
Not a fit: Patients who do not have alcohol use disorders or panic disorders are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for individuals with alcohol use disorders and panic disorders.
How similar studies have performed: While the specific approach of examining TDAG8 in the context of AUD and PD is novel, there is emerging evidence supporting the role of acid-base dysregulation in psychiatric disorders.
Where this research is happening
Chicago, UNITED STATES
- UNIVERSITY OF ILLINOIS AT CHICAGO — Chicago, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MCMURRAY, KATHERINE MILES JOHNSTON — UNIVERSITY OF ILLINOIS AT CHICAGO
- Study coordinator: MCMURRAY, KATHERINE MILES JOHNSTON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.