Investigating how acid-base balance affects fracture risk
Acid-Base Status as a Novel Risk Factor for Fractures
This study is looking at how what we eat and our body's acid-base balance might affect bone health and the risk of fractures in older adults, and it invites participants to share their dietary habits and provide samples to help uncover these connections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10792635 on NIH RePORTER |
What this research studies
This research explores the relationship between acid-base status and the risk of fractures, particularly in older adults. It examines how dietary choices and metabolic processes influence bone health and fracture incidence. By analyzing data from large cohort studies and utilizing advanced metabolomics technology, the research aims to identify how changes in acid-base balance can impact bone metabolism and increase fracture risk. Patients may be asked to provide dietary information and biological samples to help understand these associations.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older, particularly those at risk for fractures due to age or metabolic conditions.
Not a fit: Patients who are under 21 years old or those with no risk factors for fractures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary recommendations and interventions that reduce fracture risk in vulnerable populations.
How similar studies have performed: Previous research has indicated that dietary and metabolic factors can influence bone health, suggesting that this approach may yield valuable insights.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Paik, Julie — Brigham and Women's Hospital
- Study coordinator: Paik, Julie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.