Investigating how acetate can improve blood vessel function in older adults
Translational Studies of the Short-Chain Fatty Acid Acetate for Improving Age-Associated Arterial Dysfunction
This study is looking at how a substance called acetate might help improve blood vessel health in older adults, with the hope of finding new ways to prevent heart problems, and if successful, it will involve people in trials to see how it works for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10834128 on NIH RePORTER |
What this research studies
This research focuses on the effects of acetate, a short-chain fatty acid, on improving arterial function in older adults, which is crucial for preventing cardiovascular diseases. The study will first test acetate supplementation in aged mice to confirm its efficacy before moving on to human trials. By enhancing our understanding of how dietary components can influence cardiovascular health, this research aims to provide insights into potential dietary interventions for age-related arterial dysfunction. Participants may be involved in trials assessing the impact of acetate on their vascular health.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 21 and above who may be experiencing age-related arterial dysfunction.
Not a fit: Patients who are younger than 21 or those with acute cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary recommendations or supplements that significantly improve cardiovascular health in older adults.
How similar studies have performed: Previous research has shown promising results with short-chain fatty acids in improving various health outcomes, suggesting potential for success in this novel application.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Brunt, Vienna E — University of Colorado Denver
- Study coordinator: Brunt, Vienna E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.