Investigating how a specific transporter affects nerve cell protection
Official title: Role of uptake2 in neuroprotective signaling
Funded at City College of New York · NIH-11232048 · Data updated 2026-11-12
This study is looking at how a special transporter can help certain compounds protect and encourage the healing of nerve cells, especially after spinal cord injuries, which could lead to new treatments that help people recover from nerve damage.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | City College of New York NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | January 1, 2025 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $23,027 |
| NIH project number | 3R16NS129675-03S1 |
| Project ID | NIH-11232048 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with spinal cord injuries or conditions that affect nerve cell health.
✕Less likely to help
Patients with conditions unrelated to nerve cell damage or those who do not have spinal cord injuries may not benefit from this research.
What this research studies
This research explores the role of a transporter called Uptake2 in enhancing the protective effects of certain compounds on nerve cells. By testing these compounds in a controlled cellular model, the study aims to understand how they can promote the regrowth of damaged nerve cells, particularly in the context of spinal cord injuries. The project also focuses on the molecular mechanisms involved in this process, which could lead to new treatments for nerve damage. Patients may benefit from advancements in neuroprotective therapies derived from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance nerve cell protection and promote recovery from spinal cord injuries.
How similar studies have gone: Previous research has shown promise in using neuroprotective compounds for nerve regeneration, suggesting that this approach could yield beneficial results.
Where this research is happening
-
City College of New York
New York, United States Active
Researchers
- Principal investigator: Undieh, Ashiwel S — City College of New York
- Study coordinator: Undieh, Ashiwel S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.