Investigating how a specific RNA affects colon cancer growth
Mechanisms of lincDUSP Oncogenic Effects in Colon Cancer
This study is looking at a specific RNA called lincDUSP to see how it affects colon cancer growth, with the hope of finding new ways to treat the disease that could help patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10683922 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of a long intergenic non-coding RNA, known as lincDUSP, in the development of colon cancer. By studying how lincDUSP influences gene regulation and tumor behavior, researchers aim to uncover new therapeutic targets for treatment. The project involves both laboratory experiments and in vivo models to assess the impact of lincDUSP on cancer cell proliferation and survival. Patients may benefit from insights gained that could lead to more effective treatments for colon cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with colon cancer, particularly those experiencing treatment failure or recurrence.
Not a fit: Patients with non-cancerous conditions or those without colon cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that improve treatment outcomes for colon cancer patients.
How similar studies have performed: Other research has shown promise in targeting non-coding RNAs for cancer treatment, indicating that this approach could be a viable avenue for further exploration.
Where this research is happening
Cleveland, United States
- Case Western Reserve University — Cleveland, United States (Active)
Researchers
- Principal investigator: Laframboise, Thomas Louis — Case Western Reserve University
- Study coordinator: Laframboise, Thomas Louis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.