Investigating how a specific protein affects the invasion of glioblastoma cells
Analyzing Adhesion and Signaling Functions for PTPN12 in Invasive Glioma Cells
This study is looking at how a specific protein affects the growth and spread of glioblastoma, a tough type of brain cancer, to help find better treatments for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11004603 on NIH RePORTER |
What this research studies
This research focuses on glioblastoma, a highly aggressive brain cancer that often resists treatment. The study aims to understand the mechanisms that allow certain invasive cancer cells to grow and spread within the brain. Researchers will explore the role of a protein called PTP-PEST in regulating the behavior of these invasive cells, particularly how it interacts with other proteins involved in cell adhesion and signaling. By using genetic and biochemical methods, the team hopes to uncover new insights that could lead to better treatment strategies for glioblastoma patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with glioblastoma who are experiencing treatment resistance.
Not a fit: Patients with non-invasive forms of brain tumors or those not diagnosed with glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic targets that improve treatment outcomes for patients with glioblastoma.
How similar studies have performed: Previous research has shown promise in targeting similar pathways in cancer treatment, suggesting potential for success in this approach.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Mccarty, Joseph H — University of Tx Md Anderson Can Ctr
- Study coordinator: Mccarty, Joseph H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.