Investigating how a specific protein affects pancreatic cancer growth
Official title: The Role of Guanine Exchange Factors in Pancreatic Ductal Adenocarcinoma (PDAC)
Funded at Wayne State University · NIH-10987453 · Data updated 2026-11-12
This study is looking at how a protein called RCC1 affects the growth of pancreatic cancer, with the hope that understanding its role could help develop new treatments for patients facing this tough diagnosis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $50,474 |
| NIH project number | 1F99CA294132-01 |
| Project ID | NIH-10987453 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with pancreatic ductal adenocarcinoma.
✕Less likely to help
Patients with other types of cancer or those without pancreatic cancer may not benefit from this research.
What this research studies
This research focuses on pancreatic ductal adenocarcinoma (PDAC), a type of cancer known for its poor prognosis and limited treatment options. The study aims to understand the role of a protein called RCC1 in the growth and progression of PDAC by examining how it influences cellular processes and metabolism. Using advanced techniques like transcriptomics and metabolomics, researchers will explore how changes in RCC1 levels affect cancer cell behavior and survival. Patients may benefit from insights that could lead to new therapeutic strategies targeting this protein.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for patients with pancreatic cancer.
How similar studies have gone: While the specific role of RCC1 in PDAC is not fully understood, similar research approaches have shown promise in other cancer types.
Where this research is happening
-
Wayne State University
Detroit, United States Active
Researchers
- Principal investigator: Bannoura, Sahar — Wayne State University
- Study coordinator: Bannoura, Sahar
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.