Investigating how a specific protein affects lung cell function and repair.
MYRF as an Entry Point to Study Mesothelium Function in Lung Development and Injury Repair
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11016948
This study is looking at how a protein called MYRF helps the cells that line the lungs work, especially after injuries, to find better ways to treat lung problems like congenital diaphragmatic hernia, which could help patients breathe easier and improve their lung health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11016948 on ClinicalTrials.gov |
What this research studies
This research focuses on the mesothelium, a crucial cell layer that lines the lungs and other organs, to understand its role in lung development and repair after injury. The study examines the Myelin Regulatory Factor (MYRF), a protein that may influence how these cells function, especially in conditions like congenital diaphragmatic hernia. By exploring how MYRF affects lung cells, the research aims to uncover new insights into lung health and potential treatments for related conditions. Patients may benefit from improved understanding and therapies for lung injuries and diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with congenital diaphragmatic hernia or other lung-related conditions.
Not a fit: Patients with non-lung related conditions or those who do not have any respiratory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for lung injuries and conditions affecting lung function.
How similar studies have performed: Previous research has shown promising results in understanding lung cell functions, but this specific approach focusing on MYRF is relatively novel.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SUN, XIN — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: SUN, XIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.