Investigating how a specific protein affects heart health
The Role of m6A Binding Protein YTHDF1 in Cardiac Homeostasis
This study is looking at a protein called YTHDF1 to see how it helps keep the heart healthy and may prevent heart failure, with the hope of finding new ways to treat heart disease and improve outcomes for patients.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10911812 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of a protein called YTHDF1 in maintaining heart health and preventing heart failure. The study aims to uncover how this protein interacts with messenger RNA to help the heart adapt to stress and prevent pathological changes. By exploring the molecular pathways involved, the research seeks to identify potential new therapeutic targets that could reverse heart remodeling and improve patient outcomes. Patients may benefit from insights gained into heart disease mechanisms and potential new treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a history of heart disease or those at risk of developing heart failure.
Not a fit: Patients with non-cardiac conditions or those without any risk factors for heart disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve heart function and survival for patients with heart disease.
How similar studies have performed: Other research has shown promise in targeting molecular pathways in heart disease, suggesting that this approach could yield significant insights.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Golubeva, Volha — Ohio State University
- Study coordinator: Golubeva, Volha
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.