Investigating how a specific ion channel affects obesity and metabolic health
Ano4 and Metabolic Health
This study is looking at how a specific protein called Anoctamin 4 affects eating habits and weight control, which can help us find new ways to manage obesity and related health issues like diabetes and heart disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11072849 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of the Anoctamin 4 (Ano4) ion channel in regulating feeding behavior and body weight control, which are critical factors in obesity and related chronic conditions like diabetes and cardiovascular disease. The study will utilize various models, including genetic editing techniques, to explore how changes in the Ano4 gene affect energy balance and glucose metabolism. By examining the physiological functions of Ano4 in specific brain neurons, the research aims to uncover potential therapeutic targets for obesity management.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with obesity or related metabolic disorders who may benefit from new treatment approaches.
Not a fit: Patients who are not affected by obesity or metabolic disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating obesity and its associated health issues.
How similar studies have performed: Previous research has shown promising results in understanding the genetic and neural mechanisms of obesity, suggesting that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Xu, Yong — Baylor College of Medicine
- Study coordinator: Xu, Yong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.