Investigating how a specific cellular process affects aging and cell health
Role of Chaperone-Mediated Autophagy in Cellular Senescence
This study is looking at how a process called chaperone-mediated autophagy (CMA) affects aging and the buildup of old cells in our bodies, with the hope of finding ways to improve health and longevity as we get older.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-10899927 on NIH RePORTER |
What this research studies
This research explores the relationship between chaperone-mediated autophagy (CMA) and cellular senescence, which are both important factors in the aging process. It aims to understand how changes in CMA activity may influence the accumulation of senescent cells, which can lead to various age-related diseases. By examining the role of CMA in the clearance of these cells, the research seeks to uncover potential mechanisms that contribute to aging and cellular dysfunction. Patients may benefit from insights gained about how to enhance cellular health and longevity.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing age-related health issues or those with conditions linked to cellular senescence.
Not a fit: Patients who are young and do not have any age-related conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving cellular health and potentially delaying the onset of age-related diseases.
How similar studies have performed: While the specific interplay between CMA and senescence is less explored, related research has shown promise in understanding cellular aging and its implications for health.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Sereda, Rebecca Z — Albert Einstein College of Medicine
- Study coordinator: Sereda, Rebecca Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.