Investigating how a sodium channel affects pain from chemotherapy
Sodium Channel Nav1.6 in Chemotherapy-Induced Pain
This study is looking at how a specific sodium channel, NaV1.6, might influence the pain some people feel during chemotherapy, with the hope of finding better, non-opioid ways to help manage that pain based on individual differences.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Connecticut Healthcare System NIH-funded |
| Lab location | 1 site (West Haven, United States) |
| Project ID | NIH-10938004 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of the sodium channel NaV1.6 in causing pain related to chemotherapy treatments. By examining genetic variations of NaV1.6, the study aims to determine how these differences may affect a patient's experience of pain during chemotherapy. The research combines various scientific approaches, including molecular genetics and sensory neuron physiology, to explore potential personalized treatment strategies. Ultimately, the goal is to develop non-opioid treatments that can help manage chemotherapy-induced pain more effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research are adult cancer patients who experience pain as a side effect of chemotherapy.
Not a fit: Patients who are not undergoing chemotherapy or do not experience pain related to their treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies for cancer patients undergoing chemotherapy.
How similar studies have performed: Previous research has shown promising results in understanding the role of sodium channels in pain, suggesting that this approach could yield valuable insights.
Where this research is happening
West Haven, United States
- VA Connecticut Healthcare System — West Haven, United States (Active)
Researchers
- Principal investigator: Dib-Hajj, Sulayman D — VA Connecticut Healthcare System
- Study coordinator: Dib-Hajj, Sulayman D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.