Investigating how a protein affects fat burning and energy regulation

NNAT in metabolic regulation

NIH-funded research University of California at Davis · NIH-10879113

This study is looking at how a protein called Nnat helps fat cells burn energy and manage sugar levels, especially in kids under 11, to find new ways to help treat obesity.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10879113 on NIH RePORTER

What this research studies

This research focuses on understanding the role of a specific protein, Nnat, in regulating energy metabolism and thermogenesis in fat cells. By studying how Nnat interacts with other cellular components, the researchers aim to uncover new mechanisms that control fat burning and glucose levels in the body. The research involves both laboratory experiments and analyses of how these processes may differ in children under 11 years old. The ultimate goal is to develop new strategies for treating obesity by enhancing the body's ability to burn fat.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who are struggling with obesity or related metabolic issues.

Not a fit: Patients who are not within the age range of 0-11 years or those without obesity-related conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to innovative treatments for obesity that promote fat burning rather than just appetite suppression.

How similar studies have performed: Previous research has shown promise in targeting thermogenic mechanisms for obesity treatment, suggesting that this approach could be viable.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.