Investigating how a hormone affects heart health during stress

Role of arginine-vasopressin and V1A receptor in psychosocial stress-induced myocardial injury

NIH-funded research University of Texas Rio Grande Valley · NIH-10902002

This study is looking at how a hormone called arginine-vasopressin might help protect your heart during stressful times, especially if you experience anxiety or feel socially isolated, and it could lead to better understanding for both animals and people.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Rio Grande Valley NIH-funded
Lab location1 site (Edinburg, United States)
Project IDNIH-10902002 on NIH RePORTER

What this research studies

This research explores the role of arginine-vasopressin (AVP) and its receptor in the heart's response to psychosocial stress. It aims to understand how stress-related factors like anxiety and social isolation can lead to heart problems such as myocardial infarction. By studying the interactions between the brain and heart, the researchers hope to identify how AVP can help protect heart function during stressful situations. The study involves both animal models and potential implications for human health.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing high levels of psychosocial stress, particularly those with a history of heart issues.

Not a fit: Patients without any psychosocial stress or those who do not have cardiovascular risk factors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that protect the heart from stress-induced damage.

How similar studies have performed: Previous research has shown promising results in understanding the role of stress hormones in heart health, suggesting that this approach could yield valuable insights.

Where this research is happening

Edinburg, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.