Investigating how a hormone affects heart and metabolic health based on genetics.
Atrial Natriuretic Peptide and Regulation of Cardiometabolic Health: A Genotype-Guided Human Physiological Study
This study is looking at how a hormone called atrial natriuretic peptide (ANP) affects how our bodies use sugar and manage energy, especially in people with different genetic backgrounds, to help us understand better ways to support heart and metabolic health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-11083084 on NIH RePORTER |
What this research studies
This research explores the role of atrial natriuretic peptide (ANP) in regulating glucose utilization and energy balance, particularly focusing on how genetic variations influence these processes. The study will assess how individuals with different ANP genotypes respond to glucose and exercise challenges, which may affect their cardiometabolic health. By examining the interaction between genetic factors and physiological responses, the research aims to uncover new insights into managing cardiometabolic diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old, particularly those with specific genetic variants related to atrial natriuretic peptide.
Not a fit: Patients who do not have the genetic variants being studied or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized strategies for improving cardiometabolic health based on genetic profiles.
How similar studies have performed: Other research has shown promising results in understanding the role of genetic factors in metabolic health, suggesting that this approach could yield valuable insights.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Arora, Pankaj — University of Alabama at Birmingham
- Study coordinator: Arora, Pankaj
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.