Investigating how a drug may enhance antiviral immunity in older adults
mTOR Regulation of Basal Antiviral Immunity in the Elderly
This study is looking at how well a drug called RTB101 can help older adults fight off COVID-19 by boosting their immune system, and we're inviting older folks who are at higher risk to join in and share their experiences through an easy-to-use electronic diary.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tornado Therapeutics, INC. NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10704736 on NIH RePORTER |
What this research studies
This research focuses on evaluating the effectiveness of a drug called RTB101 in boosting the immune response against viral infections, particularly COVID-19, in older adults. The study aims to recruit older patients who are at higher risk of severe disease and assess the feasibility of tracking their symptoms using an electronic diary. Participants will receive either RTB101 or a placebo to compare the incidence and severity of COVID-19 symptoms. The goal is to gather preliminary data that could support larger trials in the future.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those who are quarantined and at increased risk of developing COVID-19.
Not a fit: Patients who are not elderly or those who do not have an increased risk of severe COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies against COVID-19 and other viral infections in older adults.
How similar studies have performed: Previous studies have shown that similar approaches using RTB101 have been effective in enhancing antiviral immunity in older populations.
Where this research is happening
New York, United States
- Tornado Therapeutics, INC. — New York, United States (Active)
Researchers
- Principal investigator: Mannick, Joan — Tornado Therapeutics, INC.
- Study coordinator: Mannick, Joan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.