Investigating hormone therapy to improve healing after rotator cuff repair
Official title: Sex Hormone Supplementation and Rotator Cuff Repair: A Preliminary Randomized Trial
Funded at University of Utah · NIH-11000262 · Data updated 2026-11-12
This study is looking at whether hormone therapy can help men aged 40-80 heal better after rotator cuff surgery, by comparing the effects of the therapy to a placebo, so that we can improve recovery for those with rotator cuff tears.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | December 1, 2022 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $152,460 |
| NIH project number | 5R21AR081006-03 |
| Project ID | NIH-11000262 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men aged 40-80 who have been diagnosed with sex hormone deficiency and are scheduled for rotator cuff repair surgery.
✕Less likely to help
Patients who are not men, or those who do not have sex hormone deficiency, may not benefit from this research.
What this research studies
This research focuses on improving healing outcomes for patients undergoing rotator cuff repair (RCR) by exploring the effects of hormone therapy in men aged 40-80 with sex hormone deficiency. The study will involve a randomized, placebo-controlled, double-blinded trial where participants will receive either hormone therapy or a placebo after their surgery. Researchers will assess the effectiveness of this treatment by evaluating the healing of the rotator cuff and overall surgical outcomes. The goal is to translate laboratory findings into better clinical care for patients suffering from rotator cuff tears.
Why it matters
Potential benefit: If successful, this research could lead to improved healing rates and better recovery outcomes for patients undergoing rotator cuff repair.
How similar studies have gone: Previous research has shown promising results in using hormone therapy for improving healing in similar contexts, suggesting potential for success in this study.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Chalmers, Peter — University of Utah
- Study coordinator: Chalmers, Peter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.