Investigating hookworm infection and its effects in Ghana
Translational studies of hookworm infection in Ghana
This study is looking into hookworm infections in Ghana to find out how they spread, what makes people more likely to get them, and how well current treatments work, all with the goal of helping improve care for those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11012809 on NIH RePORTER |
What this research studies
This research focuses on understanding hookworm infections, which are prevalent in sub-Saharan Africa and contribute to malnutrition and growth delays. The study will explore the epidemiology of hookworm in Ghana, identifying risk factors for infection and the effectiveness of current treatments. Researchers will also analyze genetic changes in hookworms to understand resistance to medications. By using both human and animal models, the research aims to provide insights that could improve treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals living in endemic areas of Ghana who are infected with hookworms or at risk of infection.
Not a fit: Patients who are not in endemic regions or who do not have hookworm infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for hookworm infections, improving health outcomes for affected populations.
How similar studies have performed: Previous research has shown that understanding the genetic makeup of parasites can lead to breakthroughs in treatment, suggesting this approach has potential for success.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Cappello, Michael — Yale University
- Study coordinator: Cappello, Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.