Investigating henipaviruses and their potential vaccines
Project 3 - USUHS
This study is looking at certain viruses that can make both people and animals sick, and it aims to learn more about the proteins that help these viruses infect cells, so researchers can create better vaccines and treatments for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Henry M. Jackson Fdn for the Adv Mil/med NIH-funded |
| Lab location | 1 site (Bethesda, United States) |
| Project ID | NIH-10581504 on NIH RePORTER |
What this research studies
This research focuses on understanding henipaviruses, specifically Nipah and Hendra viruses, which pose significant health threats to both humans and animals. The project aims to characterize the viral glycoproteins that are crucial for the viruses' ability to infect host cells. By studying these proteins, researchers hope to develop effective vaccines and therapeutics, as there are currently no approved treatments for infections caused by these viruses. The approach includes using recombinant viral glycoproteins in cell fusion assays to explore potential vaccine strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals at risk of exposure to henipaviruses, such as healthcare workers or those in close contact with infected animals.
Not a fit: Patients who are not at risk of exposure to henipaviruses or those with existing immunity to these viruses may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of vaccines or treatments that protect against severe infections caused by henipaviruses.
How similar studies have performed: Previous research on similar viral pathogens has shown promise in developing vaccines, indicating that this approach may yield successful outcomes.
Where this research is happening
Bethesda, United States
- Henry M. Jackson Fdn for the Adv Mil/med — Bethesda, United States (Active)
Researchers
- Principal investigator: Broder, Christopher C — Henry M. Jackson Fdn for the Adv Mil/med
- Study coordinator: Broder, Christopher C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.