Investigating heart tissue scarring using advanced MRI techniques
Assessing myocardial fibrosis with spin locked MRI
This study is looking at a new MRI method to better see heart scarring, which can help doctors understand heart diseases without needing special dyes, and it aims to improve how we monitor and treat these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11073890 on NIH RePORTER |
What this research studies
This research focuses on understanding myocardial fibrosis, a condition that can indicate various heart diseases. By utilizing a new MRI technique called spin locking or T1rho imaging, the study aims to assess heart tissue scarring more effectively without the use of contrast agents like gadolinium. The research will involve preclinical models to evaluate different MRI methods and their ability to predict myocardial fibrosis. This could lead to better monitoring of heart conditions and treatment responses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with known or suspected myocardial fibrosis or other cardiac conditions.
Not a fit: Patients without any cardiac issues or those who do not have access to advanced MRI technology may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a non-invasive method to better diagnose and monitor heart diseases, potentially improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using advanced MRI techniques for cardiac assessment, but this specific approach is relatively novel.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Dibella, Edward Vr — University of Utah
- Study coordinator: Dibella, Edward Vr
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.