Investigating heart recovery in patients with diabetes and heart failure
Official title: Understanding Myocardial Recovery in Diabetes and Heart Failure
Funded at VA Salt Lake City Healthcare System · NIH-11051762 · Data updated 2026-11-12
This study is looking at how heart function can get better in people with diabetes and heart failure who are using a special heart pump, and it aims to find out how different levels of diabetes control affect their recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Salt Lake City Healthcare System NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | October 1, 2020 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| NIH project number | 5I01CX002291-05 |
| Project ID | NIH-11051762 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with both diabetes and heart failure who are undergoing treatment with left ventricular assist devices.
✕Less likely to help
Patients without diabetes or heart failure, or those not receiving LVAD therapy, may not benefit from this research.
What this research studies
This research focuses on understanding how heart function can improve in patients who have both diabetes and heart failure, particularly those receiving left ventricular assist devices (LVAD). By analyzing human cardiac tissue and serum samples before and after LVAD therapy, researchers aim to uncover the metabolic changes that occur during recovery. The study also involves using non-radioactive tracers to explore how glucose metabolism is affected in these patients. The goal is to identify factors that contribute to better heart recovery in well-controlled diabetes compared to poorly controlled diabetes.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for heart failure patients with diabetes, enhancing their recovery and overall health outcomes.
How similar studies have gone: Previous research has shown promising results in understanding cardiac metabolism in heart failure, but this specific approach involving LVAD and diabetes is relatively novel.
Where this research is happening
-
VA Salt Lake City Healthcare System
Salt Lake City, United States Active
Researchers
- Principal investigator: Drakos, Stavros George — VA Salt Lake City Healthcare System
- Study coordinator: Drakos, Stavros George
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.