Investigating heart health in psoriasis patients using advanced imaging techniques
Advanced CV imaging and immunophenotyping to study coronary vascular health in psoriasis
['FUNDING_OTHER'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-10886114
This study is looking at how treating psoriasis with a medication called tildrakizumab can help improve heart health in people with moderate to severe psoriasis, by using advanced imaging to check their heart function and blood flow while also studying changes in their blood.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10886114 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the link between psoriasis and cardiovascular disease by using advanced imaging techniques to assess heart health. Patients with moderate to severe psoriasis will receive treatment with tildrakizumab, a medication that reduces inflammation, while their heart function and blood flow will be monitored using state-of-the-art imaging methods. The study aims to explore how reducing inflammation can improve heart health and overall symptoms in these patients. By analyzing blood samples, researchers will also investigate the cellular changes associated with psoriasis and cardiovascular risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with moderate to severe psoriasis who are at increased risk for cardiovascular disease.
Not a fit: Patients with mild psoriasis or those without cardiovascular risk factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved heart health and reduced cardiovascular risks for patients with psoriasis.
How similar studies have performed: Previous research has shown promising results in using anti-inflammatory treatments to improve cardiovascular outcomes in patients with inflammatory conditions, suggesting potential success for this approach.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WEBER, BRITTANY NICOLE — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: WEBER, BRITTANY NICOLE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.