NIH-funded research U01 cooperative agreement

Investigating heart health in mothers after pregnancy complications

Official title: Continuation of the NuMoM2b Heart Health Study

Funded at Research Triangle Institute · NIH-10905863 · Data updated 2026-11-12

This study is looking at how problems during pregnancy, like high blood pressure and having smaller babies, can impact mothers' heart health later on, and it's for women who have experienced these issues to help us learn more about their long-term health.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionResearch Triangle Institute
NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project startSeptember 1, 2023
Project endJanuary 31, 2027
Funding year2023
Award (this year)$2,129,960
NIH project number3U01HL145358-04S1
Project IDNIH-10905863 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are nulliparous women who have experienced adverse pregnancy outcomes, such as hypertensive disorders or small for gestational age births.

Less likely to help

Patients who have not experienced any pregnancy complications or who are not nulliparous may not receive any benefit from this research.

What this research studies

This research focuses on understanding how adverse pregnancy outcomes, such as high blood pressure and small for gestational age births, affect the long-term heart health of mothers. By following a large group of women who experienced these complications, the study aims to gather data on cardiovascular disease risk factors over several years. Participants will be engaged through various activities, including increased incentives for their involvement, to ensure comprehensive data collection and analysis. The research utilizes biospecimens and extensive health assessments to explore the connections between pregnancy complications and cardiovascular health.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for monitoring and reducing cardiovascular disease risk in mothers after pregnancy complications.

How similar studies have gone: Previous studies have shown success in understanding the links between pregnancy outcomes and long-term health, making this research a continuation of established findings.

Where this research is happening

  • Research Triangle Institute
    Research Triangle Park, United States
    Active

Researchers

  • Principal investigator: Mcneil, Rebecca Boehm — Research Triangle Institute
  • Study coordinator: Mcneil, Rebecca Boehm

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.